With support from the National Institutes of Health, Rout has formed the National Center for Dynamic Interactome Research, which includes several collaborating laboratories at Rockefeller and other institutions. The center is developing the methodologies required to obtain a comprehensive map of protein interactions within any organism, and to study their dynamic behaviors. This will allow researchers to explore the utility of the technology for functional elucidation of complex biological processes, with an initial focus on cell cycle control, transcription, oncogenesis, and viral infection. Rout and colleagues are also investigating nanobodies, a class of small antibody-like molecules found in camels and related species, for potential use in a rapid point-of-care diagnostic or as a therapeutic for SARS-CoV-2.
For more information, please visit the NCDIR Homepage!